Impaired early left ventricular relaxation in coronary artery disease: effects of intracornary nifedipine.

Impaired early left ventricular relaxation in coronary artery disease: effects of intracornary nifedipine.

It has been shown that the maximal rate of left ventricular (LV) relaxation is impaired in patients with coronary artery disease (CAD) under basal conditions. To test the hypothesis that this impaired LV relaxation could be related to viable but metabolically abnormal myocardium, we studied the time course of isovolumic LV pressure fall in 21 patients with CAD and in 13 control subjects under b...

Impaired Early Left Ventricular Relaxation in Coronary Artery Disease: Effects of Intracoronary Nifedipine

It has been shown that the maximal rate of left ventricular (LV) relaxation is impaired in patients with coronary artery disease (CAD) under basal conditions. To test the hypothesis that this impaired LV relaxation could be related to viable but metabolically abnormal myocardium, we studied the time course of isovolumic LV pressure fall in 21 patients with CAD and in 13 control subjects under b...

Impaired maximal rate of left ventricular relaxation in patients with coronary artery disease and left ventricular dysfunction.

It has been suggested that the rate of left ventricular (LV) relaxation is related to the inotropic state, end-systolic fiber length and peak LV pressure, but little information is available regarding the rate of LV relaxation in patients with coronary artery disease (CAD) and LV dysfunction. To assess the rate of LV relaxation we obtained high-fidelity LV pressure measurements with manometer-t...

Left ventricular function in coronary artery disease.

The Effect of Cardiac Rehabilitation on Left Ventricular Remodeling in Men and Women Patients with Coronary Artery Disease

Objective: Left ventricular (LV) remodeling is associated with increased morbidity and mortality therefore, interventions that halt or reverse ventricular remodeling are expected to prevent these clinical outcomes. The aim of the study was to assess the effects of cardiac rehabilitation program on cardiac remodeling process in patients with coronary artery disease and then compare the results b...